Freeze Drying in the Pharmaceutical, Biological and Food industry
About This Event
This 90-minute session will cover the basics of freeze drying as it relates to the pharmaceutical, biological and food industries. Specifically, this session will highlight using a scientific approach to developing an optimal formulation and lyophilization cycle for those freeze-drying in these industries.
Why Should You Attend:
This session will start with an introduction to thermal characterization including differential scanning calorimetry (DSC) and freeze-dry microscopy (FDM) and how the information gained from these techniques can be used as the foundation for optimized formulation and cycle design.
Next, we will discuss, in detail, the process of designing the freezing, primary, annealing (if used), and secondary drying protocols for the cycle. In each case, the process will be broken down to understand the correct choice of the different controllable lyopohilizer parameters including shelf temperature, chamber pressure, and hold times. Also discussed, will be some of the specialized tools that can be used to aid the development scientist in cycle development including, the sample thief, the Pirani gauge, and thermocouples.
Learning Objectives:
- Learning how to interpret a lyophilization cycle chart.
- Understanding formulation issues in regards to lyophilized products.
- Developing optimal conditions for freezing, primary, and secondary drying.
- Distinguish between amorphous and crystalline components and how they affect cycle design.
- Understanding the need and techniques of characterizing the dried solids.
Event Details:
Date: October 10, 2012
Time: 10:00 AM-11:30 AM PDT
Cost: $249 per attendee per computer terminal
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