Advanced Cell Culture & Fermentation - Process Development & Manufacture

This webinar covers advanced topics in the development and manufacture of cell culture and fermentation processes, including important elements of reactor design; technical aspects of development and scale-up; strategies for increasing titers; requirements for successful technology transfer and compliant operations.

Why Should You Attend:

The presentation will start by covering the bioreactor design, and will include the major categories of bioreactor models, applications for each design, as well as common types of agitators and impellers. This will lead into a discussion of the engineering involved in the development and scale-up of upstream processes, including selection of operating parameters and in-process specifications, and a description of models used for power input, as well as heat and oxygen transfer. Approaches to experimental design and quality by design (QBD) will also be included. Next, strategies for increasing titer, or product formation, at both the genetic and process levels, will be presented. The final topics of this workshop include recommendations for successful technology transfer from R&D to manufacturing, as well as a discussion of the applicable health agency guidelines.

Learning objectives:

• Learn different approaches for increasing titers
• Identify appropriate bioreactor and fermentor configuration types
• Understand agitator and impeller design requirements
• Define critical and non-critical process parameters
• Apply basic scale-up models pertaining to power input and oxygen transfer
• Understand principles of quality by design (QBD)
• Follow health agency requirements

For Registration:

http://www.complianceonline.com/ecommerce/control/trainingFocus/~product_id=702747?channel=worldconf